Christopher Lloyd’s Addictions; Antipsychotics and Cancer; Detransition Clinic Opens


Actor Christopher Lloyd, 88, opened up about his struggles with addiction to cocaine, alcohol, and marijuana during the 1970s and 1980s. (USA Today)

Health Secretary Robert F. Kennedy Jr. reportedly plans to bypass a candidate recommended by the NIH director to lead the National Institute of Mental Health and instead is considering one whose work centers on metabolic psychiatry, a field that uses ketogenic diets to treat mental illness. (Becker’s Behavioral Health)

Politico looked at the Trump administration’s efforts to get psychedelics to millions of veterans.

Meanwhile, an HHS press release praised the administration for the decline in opioid overdose deaths.

A national survey found two-thirds of adults were unaware of medications for alcohol use disorder (MAUD), and 16.4% said it was inappropriate to use MAUD as part of treatment. (JAMA Internal Medicine)

Antipsychotics for schizophrenia were associated with lower all-cause mortality and relapse rates compared with nonuse, but higher risks for fractures, lung infections, and cancer, a systematic review and meta-analysis found. (Molecular Psychiatry)

Reduced brain beta-wave activity may be a neural marker for schizophrenia, according to a preliminary study. (Science Advances)

An estimated 18.1 million people globally had anorexia or bulimia nervosa in 2023, representing a major contributor to nonfatal health loss. (JAMA Psychiatry)

An investigational nasal spray of the psychedelic mebufotenin benzoate was effective and well-tolerated in a phase IIb trial of patients with treatment-resistant depression. (JAMA)

A self-controlled case series suggested attention deficit-hyperactivity disorder medications were unlikely to be the primary driver behind elevated self-harm rates in patients. (BMJ Mental Health)

Rapport Therapeutics said its investigational acute bipolar mania drug candidate RAP-219 met all primary and secondary endpoints in a phase II trial.

The nation’s first detransition clinic, at Texas Children’s Hospital, is now open, said Attorney Gen­er­al Ken Paxton.

American Psychiatric Association (APA) Publishing released three new titles for clinicians, including guidance on positive psychiatry and adolescent clinical interviewing.

The APA will host a virtual training session to help physicians address gambling disorder on Nov. 10.

How does an 80-year-old dementia expert keep his brain sharp? The Washington Post profiled the Mayo Clinic’s Ron Petersen, MD, PhD.

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